Catalog: YT2777
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
MKP-7
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
73kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
MKP-7 Polyclonal Antibody detects endogenous levels of MKP-7 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
73kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human DUSP16. AA range:571-620
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Specificity:
MKP-7 Polyclonal Antibody detects endogenous levels of MKP-7 protein.
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Gene Name:
DUSP16
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Protein Name:
Dual specificity protein phosphatase 16
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Other Name:
DUSP16 ;
KIAA1700 ;
MKP7 ;
Dual specificity protein phosphatase 16 ;
Mitogen-activated protein kinase phosphatase 7 ;
MAP kinase phosphatase 7 ;
MKP-7
KIAA1700 ;
MKP7 ;
Dual specificity protein phosphatase 16 ;
Mitogen-activated protein kinase phosphatase 7 ;
MAP kinase phosphatase 7 ;
MKP-7
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Background:
dual specificity phosphatase 16(DUSP16) Homo sapiens This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010],
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Function:
Catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,Catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,Function:Involved in the inactivation of MAP kinases.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 rhodanese domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
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Cellular Localization:
Cytoplasm. Nucleus. Cytoplasmic vesicle. After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles.
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Tissue Expression:
Bone marrow,Brain,Duodenum,PCR rescued clones,
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Research Areas:
>>MAPK signaling pathway
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT2777
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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