The antiserum was produced against synthesized peptide derived from human VAMP-1/2/3. AA range:21-70

VAMP-1/2/3 Polyclonal Antibody detects endogenous levels of VAMP-1/2/3 protein.

VAMP1/VAMP2/VAMP3

Vesicle-associated membrane protein 1/2/3

VAMP1 ;
SYB1 ;
Vesicle-associated membrane protein 1 ;
VAMP-1 ;
Synaptobrevin-1 ;
VAMP2 ;
SYB2 ;
Vesicle-associated membrane protein 2 ;
VAMP-2 ;
Synaptobrevin-2 ;
VAMP3 ;
SYB3 ;
Vesicle-associated membrane protein 3 ;
VAMP-3 ;
Cellubrevin ;
CEB ;
Synaptob

Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014],

Function:Involved in the targeting and/or fusion of transport vesicles to their target membrane.,similarity:Belongs to the synaptobrevin family.,similarity:Contains 1 v-SNARE coiled-coil homology domain.,subunit:Interacts with VAPA and VAPB.,tissue specificity:Nervous system, skeletal muscle and adipose tissue.,

[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type IV membrane protein . Cell junction, synapse, synaptosome .; [Isoform 2]: Cytoplasmic vesicle membrane ; Single-pass type IV membrane protein . Cell junction, synapse, synaptosome .; [Isoform 3]: Mitochondrion outer membrane; Single-pass type IV membrane protein .

>>SNARE interactions in vesicular transport