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Catalog: YN0514
Size
Price
Status
Qty.
200μL
$450.00
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100μL
$280.00
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40μL
$150.00
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Main Information
Target

CANB1

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, ELISA

MW

18kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
CANB1 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
18kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
CANB1 Polyclonal Antibody detects endogenous levels of protein.
show all
Gene Name:
PPP3R1 CNA2 CNB
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Protein Name:
Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1)
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Database Link:
Organism Gene ID SwissProt
Human 5534; P63098;
Mouse Q63810;
Rat P63100;
Background:
function:Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.,miscellaneous:This protein has four functional calcium-binding sites.,similarity:Belongs to the calcineurin regulatory subunit family.,similarity:Contains 4 EF-hand domains.,subunit:Composed of a catalytic subunit (A) and a regulatory subunit (B).,
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Function:
Function:Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.,miscellaneous:This protein has four functional calcium-binding sites.,similarity:Belongs to the calcineurin regulatory subunit family.,similarity:Contains 4 EF-hand domains.,subunit:Composed of a catalytic subunit (A) and a regulatory subunit (B).,
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Cellular Localization:
Cytoplasm, cytosol . Cell membrane . Cell membrane, sarcolemma . Cell membrane ; Lipid-anchor . Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocyte hypertrophy. .
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Tissue Expression:
Blood,Fetal brain cortex,
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Research Areas:
>>MAPK signaling pathway ;
>>Calcium signaling pathway ;
>>cGMP-PKG signaling pathway ;
>>Oocyte meiosis ;
>>Cellular senescence ;
>>Wnt signaling pathway ;
>>Axon guidance ;
>>VEGF signaling pathway ;
>>Osteoclast differentiation ;
>>C-type lectin receptor signaling pathway ;
>>Natural killer cell mediated cytotoxicity ;
>>Th1 and Th2 cell differentiation ;
>>Th17 cell differentiation ;
>>T cell receptor signaling pathway ;
>>B cell receptor signaling pathway ;
>>Long-term potentiation ;
>>Glutamatergic synapse ;
>>Oxytocin signaling pathway ;
>>Glucagon signaling pathway ;
>>Renin secretion ;
>>Alzheimer disease ;
>>Amyotrophic lateral sclerosis ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Amphetamine addiction ;
>>Tuberculosis ;
>>Human cytomegalovirus infection ;
>>Human T-cell leukemia virus 1 infection ;
>>Kaposi sarcoma-associated herpesvirus infection ;
>>Human immunodeficiency virus 1 infection ;
>>PD-L1 expression and PD-1 checkpoint pathway in cancer ;
>>Lipid and atherosclerosis
show all
Signaling Pathway
Cellular Processes >> Cell growth and death >> Cellular senescence Organismal Systems >> Immune system >> Natural killer cell mediated cytotoxicity Organismal Systems >> Immune system >> T cell receptor signaling pathway Organismal Systems >> Immune system >> Th1 and Th2 cell differentiation Organismal Systems >> Immune system >> Th17 cell differentiation Organismal Systems >> Immune system >> B cell receptor signaling pathway Organismal Systems >> Endocrine system >> Glucagon signaling pathway Organismal Systems >> Endocrine system >> Oxytocin signaling pathway Organismal Systems >> Nervous system >> Glutamatergic synapse Organismal Systems >> Development and regeneration >> Osteoclast differentiation Human Diseases >> Cancer: overview >> PD-L1 expression and PD-1 checkpoint pathway in cancer Human Diseases >> Neurodegenerative disease >> Alzheimer disease Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis Human Diseases >> Neurodegenerative disease >> Prion disease Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases Environmental Information Processing >> Signal transduction >> MAPK signaling pathway Environmental Information Processing >> Signal transduction >> Wnt signaling pathway Environmental Information Processing >> Signal transduction >> VEGF signaling pathway Environmental Information Processing >> Signal transduction >> Calcium signaling pathway Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway
Catalog: YN0514
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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