Catalog: YM4915
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
40μL
$190.00
In stock
0
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Collected
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Main Information
Target
Annexin I
Host Species
Mouse
Reactivity
Human, Mouse, Rat
Applications
IHC, WB, IF, ELISA
MW
38kD (Calculated)
37kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
This antibody detects endogenous levels of Annexin A1 protein.
Purification
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
38kD
MW(Observed)
37kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT-ANXA1
Isotype
Mouse IgG1/Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Annexin A1 AA range: 250-346
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Specificity:
This antibody detects endogenous levels of Annexin A1 protein.
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Gene Name:
ANXA1 ANX1 LPC1
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Protein Name:
Annexin A1 (Annexin I) (Annexin-1) (Calpactin II) (Calpactin-2) (Chromobindin-9) (Lipocortin I) (Phospholipase A2 inhibitory protein) (p35)
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Background:
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014],
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Function:
Domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,Function:Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.,PTM:Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity.,similarity:Belongs to the annexin family.,similarity:Contains 1 annexin repeat.,similarity:Contains 2 annexin repeats.,similarity:Contains 4 annexin repeats.,subcellular location:Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages.,subunit:Homodimer in placenta (20%); linked by transglutamylation. Interacts with DYSF.,
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Cellular Localization:
Cytoplasmic, Nuclear
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Reference Citation({{totalcount}})
Catalog: YM4915
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
40μL
$190.00
In stock
0
Add to cart
Collected
Collect
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