Synaptophysin Rabbit pAb

-YT4500

Catalog: YT4500
Size
Price
Status
Qty.
200μL
$450.00
In stock

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100μL
$280.00
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40μL
$150.00
In stock

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Main Information
Target

Synaptophysin

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF, ELISA

MW

38kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
SYP Polyclonal Antibody detects endogenous levels of SYP protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
38kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
Related Products
Primary Antibodies
Synaptophysin Rabbit pAb
YT4500

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ELISA Kits
Total SYP Cell-Based Colorimetric ELISA Kit
KA3385C

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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human Synaptophysin. AA range:101-150
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Specificity:
SYP Polyclonal Antibody detects endogenous levels of SYP protein.
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Gene Name:
SYP
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Protein Name:
Synaptophysin
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Other Name:
SYP ;
Synaptophysin ;
Major synaptic vesicle protein p38
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Database Link:
Organism Gene ID SwissProt
Human 6855; P08247;
Mouse 20977; Q62277;
Rat 24804; P07825;
Background:
This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011],
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Function:
Domain:The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.,Function:Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.,online information:Synaptophysin entry,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the synaptophysin/synaptobrevin family.,similarity:Contains 1 MARVEL domain.,subunit:Homohexamer or homotetramer.,tissue specificity:Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.,
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Cellular Localization:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptosome .
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Catalog: YT4500
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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