Catalog: YT0568
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
C3aR
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
MW
54kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
C3aR Polyclonal Antibody detects endogenous levels of C3aR protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
54kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human C3AR1. AA range:175-224
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Specificity:
C3aR Polyclonal Antibody detects endogenous levels of C3aR protein.
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Gene Name:
C3AR1
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Protein Name:
C3a anaphylatoxin chemotactic receptor
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Other Name:
C3AR1 ;
AZ3B ;
C3R1 ;
HNFAG09 ;
C3a anaphylatoxin chemotactic receptor ;
C3AR ;
C3a-R
AZ3B ;
C3R1 ;
HNFAG09 ;
C3a anaphylatoxin chemotactic receptor ;
C3AR ;
C3a-R
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Background:
C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016],
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Function:
Function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.,
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Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Tissue Expression:
Research Areas:
>>Neuroactive ligand-receptor interaction ;
>>Complement and coagulation cascades ;
>>Alcoholic liver disease ;
>>Staphylococcus aureus infection ;
>>Coronavirus disease - COVID-19
>>Complement and coagulation cascades ;
>>Alcoholic liver disease ;
>>Staphylococcus aureus infection ;
>>Coronavirus disease - COVID-19
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Reference Citation({{totalcount}})
Catalog: YT0568
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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