Catalog: YN0554
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
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Main Information
Target
CBPA6
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
48kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
CBPA6 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
48kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
CBPA6 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
CPA6 CPAH
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Protein Name:
Carboxypeptidase A6 (Carboxypeptidase B)
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Background:
The gene encodes a member of the peptidase M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which catalyzes the release of large hydrophobic C-terminal amino acids. This enzyme has functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Mutations in this gene may be linked to epilepsy and febrile seizures, and a translocation t(6;8)(q26;q13) involving this gene has been associated with Duane retraction syndrome. [provided by RefSeq, May 2016],
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Function:
Catalytic activity:Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.,cofactor:Binds 1 zinc ion per subunit.,Disease:A chromosomal aberration disrupting CPA6 was found in a patient with Duane retraction syndrome (DURS) [MIM:126800]. Translocation t(6;8)(q26;q13).,similarity:Belongs to the peptidase M14 family.,
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Cellular Localization:
Secreted, extracellular space, extracellular matrix .
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Tissue Expression:
Expressed in the hippocampus, nucleus raphe, and cortex.
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Reference Citation({{totalcount}})
Catalog: YN0554
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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