Catalog: YT7864
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
Adipsin
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
28kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:1000-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Human Adipsin
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
28kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Adipsin AA range: 101-150
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Specificity:
This antibody detects endogenous levels of Human Adipsin
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Gene Name:
CFD DF PFD
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Protein Name:
Adipsin
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Other Name:
Complement factor D ;
Adipsin ;
C3 convertase activator ;
Properdin factor D ;
Adipsin ;
C3 convertase activator ;
Properdin factor D ;
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Database Link:
Background:
catalytic activity:Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.,disease:Defects in CFD are the cause of complement factor D deficiency [MIM:134350]. This deficiency predisposes to invasive meningococcal disease.,function:Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.,online information:CFD mutation db,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,
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Function:
immune effector process, activation of immune response, acute inflammatory response, activation of plasma proteins involved in acute inflammatory response, positive regulation of immune system process, proteolysis, defense response, inflammatory response, immune response, complement activation, complement activation, alternative pathway, humoral immune response, cell surface receptor linked signal transduction, Notch signaling pathway,response to wounding, protein processing, innate immune response, positive regulation of response to stimulus,positive regulation of immune response, protein maturation, protein maturation by peptide bond cleavage,
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Cellular Localization:
Secreted.
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Research Areas:
>>Complement and coagulation cascades ;
>>Staphylococcus aureus infection ;
>>Coronavirus disease - COVID-19
>>Staphylococcus aureus infection ;
>>Coronavirus disease - COVID-19
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Reference Citation({{totalcount}})
Catalog: YT7864
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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