Spinocerebellar ataxia
The autosomal dominant spinocerebellar ataxias (SCAs) are a group of progressive neurodegenerative diseases characterised by loss of balance and motor coordination due to the primary dysfunction of the cerebellum. Compelling evidence points to major aetiological roles for transcriptional dysregulation, protein aggregation and clearance, autophagy, the ubiquitin-proteasome system, alterations of calcium homeostasis, mitochondria defects, toxic RNA gain-of-function mechanisms and eventual cell death with apoptotic features of neurons during SCA disease progression.
Product List
- TRPC3 Rabbit pAbHuman,Mouse,RatWB,IHC,IF,ELISA
- mGluR1 Rabbit pAbHuman,Mouse,RatIHC,IF,ELISA
- GNAQ Rabbit pAbHuman,Mouse,RatWB
- PLCB1 Rabbit pAbHuman,Mouse,RatWB,ELISA
- PLC β2 Rabbit pAbHuman,Mouse,RatWB,IHC
- PLCβ3 Rabbit pAbHuman,Mouse,RatWB,IHC,IF,ELISA
- PLCβ3 (Phospho Ser1105) Rabbit pAbHuman,Mouse,RatWB,IHC,IF,ELISA
- PLCβ3 (Phospho Ser537) Rabbit pAbHuman,Mouse,RatWB,IHC,IF,ELISA
- PLCβ3 (Phospho Ser1105) Cell-Based Colorimetric ELISA KitHuman,Mouse,RatELISA
- PLCβ3 (Phospho Ser537) Cell-Based Colorimetric ELISA KitHuman,Mouse,RatELISA
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