Synthesized peptide derived from human protein . at AA range: 40-120

ADT2 Polyclonal Antibody detects endogenous levels of protein.

SLC25A5 ANT2

ADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5)

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013],

Function:Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.,miscellaneous:The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,subunit:Homodimer. Interacts with HIV-1 Vpr.,

Mitochondrion inner membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein . May localize to non-mitochondrial membranes. .

>>Calcium signaling pathway ;
>>cGMP-PKG signaling pathway ;
>>Necroptosis ;
>>Cellular senescence ;
>>Neutrophil extracellular trap formation ;
>>Alzheimer disease ;
>>Parkinson disease ;
>>Huntington disease ;
>>Spinocerebellar ataxia ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Influenza A ;
>>Human T-cell leukemia virus 1 infection ;
>>Chemical carcinogenesis - reactive oxygen species ;
>>Diabetic cardiomyopathy