Catalog: YM3378
Size
Price
Status
Qty.
200μL
$450.00
3 weeks
0
100μL
$280.00
3 weeks
0
40μL
$160.00
3 weeks
0
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Collected
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Main Information
Target
HAO1
Host Species
Mouse
Reactivity
Mouse, Rat
Applications
WB, IHC, IF,
MW
41kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:1000-2000; IF 1:200; IHC 1:50-300
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Specificity
The antibody detects endogenous HAO1 protein.
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Observed)
41kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
7G12
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Antigen&Target Information
Immunogen:
Recombinant Protein of HAO1,AA range 35-85
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Specificity:
The antibody detects endogenous HAO1 protein.
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Gene Name:
HAO1
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Protein Name:
Hydroxyacid oxidase 1
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Other Name:
Hydroxyacid oxidase 1 ;
HAOX1 ;
Glycolate oxidase ;
GOX
HAOX1 ;
Glycolate oxidase ;
GOX
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Background:
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008],
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Function:
Catalytic activity:(S)-2-hydroxy acid + O(2) = 2-oxo acid + H(2)O(2).,cofactor:FMN.,Function:Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids.,pathway:Organic acid metabolism; glycolic acid degradation; 3-phospho-D-glyceric acid from glycolic acid: step 1/4.,similarity:Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.,similarity:Contains 1 FMN hydroxy acid dehydrogenase domain.,tissue specificity:Liver.,
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Cellular Localization:
Peroxisome matrix .
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Tissue Expression:
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Research Areas:
>>Glyoxylate and dicarboxylate metabolism ;
>>Metabolic pathways ;
>>Carbon metabolism ;
>>Peroxisome
>>Metabolic pathways ;
>>Carbon metabolism ;
>>Peroxisome
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YM3378
Size
Price
Status
Qty.
200μL
$450.00
3 weeks
0
100μL
$280.00
3 weeks
0
40μL
$160.00
3 weeks
0
Add to cart
Collected
Collect
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