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Peroxisome
Peroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ether lipids and free radical detoxification. The biogenesis of peroxisomes starts with the early peroxins PEX3, PEX16 and PEX19 and proceeds via several steps. The import of membrane proteins into peroxisomes needs PEX19 for recognition, targeting and insertion via docking at PEX3. Matrix proteins in the cytosol are recognized by peroxisomal targeting signals (PTS) and transported to the docking complex at the peroxisomal membrane. Peroxisomes' deficiencies lead to severe and often fatal inherited peroxisomal disorders (PD). PDs are usually classified in two groups. The first group is disorders of peroxisome biogenesis which include Zellweger syndrome, and the second group is single peroxisomal enzyme deficiencies.
Product List
    Catalog
    Product
    Reactivity
    Applications
  • PEX16 Rabbit pAb
    Human,Mouse
    WB,ELISA
  • Peroxin 3 Rabbit pAb
    Human,Mouse,Rat
    WB,ELISA,IHC
  • Peroxin 19 Rabbit pAb
    Human,Rat,Mouse,
    WB,IHC,IF,ELISA
  • ABCD3 Rabbit pAb
    Human,Mouse,Rat
    WB,ELISA
  • Peroxin 1 Rabbit pAb
    Human,Mouse
    IHC,IF,ELISA
  • PEX6 Rabbit pAb
    Human,Rat,Mouse
    WB,ELISA
  • PEX26 Rabbit pAb
    Human,Mouse
    WB
  • Peroxin 7 Rabbit pAb
    Human,Mouse,Rat
    WB,IHC,IF,ELISA
  • Peroxin 5 Rabbit pAb
    Human,Mouse
    WB,IHC
  • PEX5R Rabbit pAb
    Human,Mouse,Rat
    WB,IHC
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