Catalog: YC0052
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
Ephrin-A2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
21kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Cleaved-Ephrin-A2 (N188) Polyclonal Antibody detects endogenous levels of fragment of activated Ephrin-A2 protein resulting from cleavage adjacent to N188.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
21kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human EFNA2. AA range:139-188
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Specificity:
Cleaved-Ephrin-A2 (N188) Polyclonal Antibody detects endogenous levels of fragment of activated Ephrin-A2 protein resulting from cleavage adjacent to N188.
show all
Gene Name:
EFNA2
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Protein Name:
Ephrin-A2
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Other Name:
EFNA2 ;
EPLG6 ;
LERK6 ;
Ephrin-A2 ;
EPH-related receptor tyrosine kinase ligand 6 ;
LERK-6 ;
HEK7 ligand ;
HEK7-L
EPLG6 ;
LERK6 ;
Ephrin-A2 ;
EPH-related receptor tyrosine kinase ligand 6 ;
LERK-6 ;
HEK7 ligand ;
HEK7-L
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Background:
This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008],
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Function:
similarity:Belongs to the ephrin family.,subunit:Binds to the receptor tyrosine kinases EPHA3, EPHA4 and EPHA5.,
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Cellular Localization:
Cell membrane ; Lipid-anchor, GPI-anchor .
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Tissue Expression:
Brain,
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Research Areas:
>>MAPK signaling pathway ;
>>Ras signaling pathway ;
>>Rap1 signaling pathway ;
>>PI3K-Akt signaling pathway ;
>>Axon guidance ;
>>MicroRNAs in cancer
>>Ras signaling pathway ;
>>Rap1 signaling pathway ;
>>PI3K-Akt signaling pathway ;
>>Axon guidance ;
>>MicroRNAs in cancer
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Signaling Pathway
Human Diseases >> Cancer: overview >> MicroRNAs in cancer
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Reference Citation({{totalcount}})
Catalog: YC0052
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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