Catalog: YT6874
Size
Price
Status
Qty.
200μL
$450.00
In stock

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100μL
$280.00
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40μL
$150.00
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Main Information
Target

PIGO

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

WB, IHC

MW

120kD (Calculated)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of PIGO at Human/Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
120kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human PIGO AA range: 950-1000
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Specificity:
This antibody detects endogenous levels of PIGO at Human/Mouse
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Gene Name:
PIGO UNQ632/PRO1249
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Protein Name:
PIGO
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Database Link:
Organism Gene ID SwissProt
Human 84720; Q8TEQ8;
Mouse Q9JJI6;
Background:
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011],
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Function:
Alternative products:Additional isoforms seem to exist,Function:Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond.,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.,subunit:Forms a complex with PIGF. PIGF is required to stabilize PIGO.,
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Cellular Localization:
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
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Research Areas:
>>Glycosylphosphatidylinositol (GPI)-anchor biosynthesis ;
>>Metabolic pathways
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Catalog: YT6874
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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