Catalog: YT2623
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
MAGE-1
Host Species
Rabbit
Reactivity
Human
Applications
WB, IHC, IF, ELISA
MW
34kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
MAGE-1 Polyclonal Antibody detects endogenous levels of MAGE-1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
34kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human MAGE-1. AA range:260-309
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Specificity:
MAGE-1 Polyclonal Antibody detects endogenous levels of MAGE-1 protein.
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Gene Name:
MAGEA1
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Protein Name:
Melanoma-associated antigen 1
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Other Name:
MAGEA1 ;
MAGE1 ;
MAGE1A ;
Melanoma-associated antigen 1 ;
Antigen MZ2-E ;
Cancer/testis antigen 1.1 ;
CT1.1 ;
MAGE-1 antigen
MAGE1 ;
MAGE1A ;
Melanoma-associated antigen 1 ;
Antigen MZ2-E ;
Cancer/testis antigen 1.1 ;
CT1.1 ;
MAGE-1 antigen
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Background:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008],
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Function:
Function:Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.,similarity:Contains 1 MAGE domain.,tissue specificity:Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.,
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Cellular Localization:
Cytoplasm. Nucleus.
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Tissue Expression:
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.
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Reference Citation({{totalcount}})
Catalog: YT2623
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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