Catalog: YT0261
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
APC1
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
IHC, IF, ELISA
MW
217kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
APC1 Polyclonal Antibody detects endogenous levels of APC1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
217kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human APC1. AA range:321-370
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Specificity:
APC1 Polyclonal Antibody detects endogenous levels of APC1 protein.
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Gene Name:
ANAPC1
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Protein Name:
Anaphase-promoting complex subunit 1
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Other Name:
ANAPC1 ;
TSG24 ;
Anaphase-promoting complex subunit 1 ;
APC1 ;
Cyclosome subunit 1 ;
Mitotic checkpoint regulator ;
Testis-specific gene 24 protein
TSG24 ;
Anaphase-promoting complex subunit 1 ;
APC1 ;
Cyclosome subunit 1 ;
Mitotic checkpoint regulator ;
Testis-specific gene 24 protein
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Background:
This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011],
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Function:
Function:Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated. Phosphorylation on Ser-355 occurs specifically during mitosis.,similarity:Belongs to the APC1 family.,similarity:Contains 4 PC repeats.,subunit:The APC/C is composed of at least 11 subunits.,
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Cellular Localization:
nucleoplasm,anaphase-promoting complex,cytosol,
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Tissue Expression:
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Research Areas:
>>Cell cycle ;
>>Oocyte meiosis ;
>>Ubiquitin mediated proteolysis ;
>>Progesterone-mediated oocyte maturation ;
>>Human T-cell leukemia virus 1 infection
>>Oocyte meiosis ;
>>Ubiquitin mediated proteolysis ;
>>Progesterone-mediated oocyte maturation ;
>>Human T-cell leukemia virus 1 infection
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT0261
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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