Catalog: YN0348
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
MOGT3
Host Species
Rabbit
Reactivity
Human
Applications
WB, ELISA
MW
37kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
MOGT3 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
37kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 10-90
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Specificity:
MOGT3 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
MOGAT3 DC7 DGAT2L7 UNQ9383/PRO34208
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Protein Name:
2-acylglycerol O-acyltransferase 3 (Acyl-CoA:monoacylglycerol acyltransferase 3) (MGAT3) (Diacylglycerol O-acyltransferase candidate 7) (hDC7) (Diacylglycerol acyltransferase 2-like protein 7) (Monoacylglycerol O-acyltransferase 3)
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Background:
Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008],
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Function:
Catalytic activity:Acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.,Catalytic activity:Acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.,Function:Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes.,pathway:Glycerolipid metabolism; triacylglycerol biosynthesis.,similarity:Belongs to the diacylglycerol acyltransferase family.,tissue specificity:Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver.,
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Cellular Localization:
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cytoplasm, perinuclear region .
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Tissue Expression:
Research Areas:
>>Glycerolipid metabolism ;
>>Metabolic pathways ;
>>Fat digestion and absorption
>>Metabolic pathways ;
>>Fat digestion and absorption
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Reference Citation({{totalcount}})
Catalog: YN0348
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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