Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016],
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Function:
Function:Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1, but not SLC2A4/GLUT4, expression.,similarity:Belongs to the heparin-binding growth factors family.,
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Cellular Localization:
Secreted .
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Tissue Expression:
Lung,
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Research Areas:
>>MAPK signaling pathway ;
>>Ras signaling pathway ;
>>Rap1 signaling pathway ;
>>Calcium signaling pathway ;
>>PI3K-Akt signaling pathway ;
>>Thermogenesis ;
>>Regulation of actin cytoskeleton ;
>>Pathways in cancer ;
>>Melanoma ;
>>Breast cancer ;
>>Gastric cancer