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CD185 (PN0449) Nb-FC recombinant antibody

-YA0604

Catalog: YA0604
Size
Price
Status
Qty.
200μg
$600.00
3 weeks

0

100μg
$340.00
3 weeks

0

40μg
$190.00
3 weeks

0

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Collected

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Main Information
Target

CD185

Reactivity

Human

Applications

Flow Cyt, ELISA

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
ELISA 1:5000-100000
Formulation
Phosphate-buffered solution
Source
Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Specificity
This recombinant monoclonal antibody can detects endogenous levels of CD185 protein.
Purification
Recombinant Expression and Affinity purified
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration
Please check the information on the tube
Modification
Unmodified
Clone Number
PN0449
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Goat Anti Mouse IgG(H+L) (HRP)
RS0001

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Antigen&Target Information
Immunogen:
Purified recombinant Human CD185
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Specificity:
This recombinant monoclonal antibody can detects endogenous levels of CD185 protein.
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Gene Name:
CXCR5 BLR1 MDR15
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Protein Name:
C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1) (Monocyte-derived receptor 15) (MDR-15) (CD antigen CD185)
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Other Name:
BLR1 ;
MDR15 ;
BLR 1 antibody ;
BLR1 antibody ;
Burkitt lymphoma receptor 1 antibody ;
Burkitt lymphoma receptor 1 GTP binding protein antibody ;
Burkitt lymphoma receptor 1 ;
GTP binding protein ;
chemokine ;
C-X-C motif ;
receptor 5 ;
antibody ;
C X C chemokine receptor type 5 antibody ;
C-X-C chemokine receptor type 5 antibody ;
CD 185 antibody ;
CD185 antibody ;
CD185 antigen antibody ;
Chemokine ;
C-X-C motif ;
receptor 5 antibody ;
Chemokine C X C motif receptor 5 antibody ;
Chemokine CXC motif receptor 5 antibody ;
Chemokine receptor 5 antibody ;
CXC chemokine receptor type 5 antibody ;
CXC R5 antibody ;
CXC-R5 antibody ;
CXCR 5 antibody ;
CXCR-5 antibody ;
Cxcr5 antibody ;
CXCR5_HUMAN antibody ;
MDR 15 antibody ;
MDR-15 antibody ;
MDR15 antibody ;
MGC117347 antibody ;
Monocyte derived receptor 15 antibody ;
Monocyte-derived receptor 15 antibody ;
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Database Link:
Organism Gene ID SwissProt
Human 3439; P32302;
Background:
CD185, also known as CXCR5, is a 42 kD G-protein coupled receptor with seven transmembrane regions. CXCR5 is expressed by mature B cells, follicular helper T cells, Burkitt’s lymphoma cells and a subset of neurons, and mediates cell migration to the B cell follicles in the secondary lymphoid organs. The ligand of CXCR5 is CXCL13 (BLC).
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Function:
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.
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Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Research Areas:
>>Cytokine-cytokine receptor interaction ;
>>PI3K-Akt signaling pathway ;
>>Necroptosis ;
>>Toll-like receptor signaling pathway ;
>>NOD-like receptor signaling pathway ;
>>RIG-I-like receptor signaling pathway ;
>>Cytosolic DNA-sensing pathway ;
>>JAK-STAT signaling pathway ;
>>Natural killer cell mediated cytotoxicity ;
>>Alcoholic liver disease ;
>>Tuberculosis ;
>>Hepatitis C ;
>>Hepatitis B ;
>>Measles ;
>>Human cytomegalovirus infection ;
>>Influenza A ;
>>Human papillomavirus infection ;
>>Kaposi sarcoma-associated herpesvirus infection ;
>>Herpes simplex virus 1 infection ;
>>Epstein-Barr virus infection ;
>>Human immunodeficiency virus 1 infection ;
>>Coronavirus disease - COVID-19 ;
>>Pathways in cancer ;
>>Autoimmune thyroid disease ;
>>Lipid and atherosclerosis
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Catalog: YA0604
Size
Price
Status
Qty.
200μg
$600.00
3 weeks

0

100μg
$340.00
3 weeks

0

40μg
$190.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service

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