Purified recombinant Human CD185

This recombinant monoclonal antibody can detects endogenous levels of CD185 protein.

CXCR5 BLR1 MDR15

C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1) (Monocyte-derived receptor 15) (MDR-15) (CD antigen CD185)

BLR1 ;
MDR15 ;
BLR 1 antibody ;
BLR1 antibody ;
Burkitt lymphoma receptor 1 antibody ;
Burkitt lymphoma receptor 1 GTP binding protein antibody ;
Burkitt lymphoma receptor 1 ;
GTP binding protein ;
chemokine ;
C-X-C motif ;
receptor 5 ;
antibody ;
C X C chemokine receptor type 5 antibody ;
C-X-C chemokine receptor type 5 antibody ;
CD 185 antibody ;
CD185 antibody ;
CD185 antigen antibody ;
Chemokine ;
C-X-C motif ;
receptor 5 antibody ;
Chemokine C X C motif receptor 5 antibody ;
Chemokine CXC motif receptor 5 antibody ;
Chemokine receptor 5 antibody ;
CXC chemokine receptor type 5 antibody ;
CXC R5 antibody ;
CXC-R5 antibody ;
CXCR 5 antibody ;
CXCR-5 antibody ;
Cxcr5 antibody ;
CXCR5_HUMAN antibody ;
MDR 15 antibody ;
MDR-15 antibody ;
MDR15 antibody ;
MGC117347 antibody ;
Monocyte derived receptor 15 antibody ;
Monocyte-derived receptor 15 antibody ;

CD185, also known as CXCR5, is a 42 kD G-protein coupled receptor with seven transmembrane regions. CXCR5 is expressed by mature B cells, follicular helper T cells, Burkitt’s lymphoma cells and a subset of neurons, and mediates cell migration to the B cell follicles in the secondary lymphoid organs. The ligand of CXCR5 is CXCL13 (BLC).

Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

Cell membrane; Multi-pass membrane protein.

Expressed in NK cell subsets (at protein level) (PubMed:21825173, PubMed:94322, PubMed:948526). Expressed in memory/effector CD8-positive alpha-beta T cell subsets (at protein level) (PubMed:12387742, PubMed:2952657). Expressed in melanoma-specific cytotoxic T cell clones (at protein level) (PubMed:948526). Expressed in terminally differentiated cytotoxic gamma-delta T cells (at protein level) (PubMed:2952657). KLRD1-KLRC1 and KLRD1-KLRC2 are differentially expressed in NK and T cell populations, with only minor subsets expressing both receptor complexes (at protein level) (PubMed:2952657).