Catalog: YA0545
Size
Price
Status
Qty.
200μg
$600.00
3 weeks
0
100μg
$340.00
3 weeks
0
40μg
$190.00
3 weeks
0
Add to cart
Collected
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Main Information
Target
CD134
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
ELISA 1:5000-100000
Formulation
Phosphate-buffered solution
Source
Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Specificity
This recombinant monoclonal antibody can detects endogenous levels of CD134 protein.
Purification
Recombinant Expression and Affinity purified
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration
Please check the information on the tube
Modification
Unmodified
Clone Number
PN0303
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RS0001
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Antigen&Target Information
Immunogen:
Purified recombinant Human CD134
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Specificity:
This recombinant monoclonal antibody can detects endogenous levels of CD134 protein.
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Gene Name:
TNFRSF4 TXGP1L
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Protein Name:
Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134)
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Other Name:
ACT 35 antibody ;
ACT35 antibody ;
ACT35 antigen antibody ;
ATC35 antigen antibody ;
CD 134 antibody ;
CD134 antibody ;
CD134 antigen antibody ;
IMD16 antibody ;
Lymphoid activation antigene ACT35 antibody ;
OX 40 antibody ;
OX40 antibody ;
OX40 antigen antibody ;
OX40 cell surface antigen antibody ;
OX40 homologue antibody ;
OX40L receptor antibody ;
TAX transcriptionally activated glycoprotein 1 receptor antibody ;
TAX transcriptionally-activated glycoprotein 1 receptor antibody ;
TNF receptor superfamily member 4 antibody ;
TNFRSF 4 antibody ;
TNFRSF4 antibody ;
TNR4_HUMAN antibody ;
Tumor necrosis factor receptor superfamily member 4 antibody ;
Txgp 1l antibody ;
Txgp1 antibody ;
Txgp1l antibody
ACT35 antibody ;
ACT35 antigen antibody ;
ATC35 antigen antibody ;
CD 134 antibody ;
CD134 antibody ;
CD134 antigen antibody ;
IMD16 antibody ;
Lymphoid activation antigene ACT35 antibody ;
OX 40 antibody ;
OX40 antibody ;
OX40 antigen antibody ;
OX40 cell surface antigen antibody ;
OX40 homologue antibody ;
OX40L receptor antibody ;
TAX transcriptionally activated glycoprotein 1 receptor antibody ;
TAX transcriptionally-activated glycoprotein 1 receptor antibody ;
TNF receptor superfamily member 4 antibody ;
TNFRSF 4 antibody ;
TNFRSF4 antibody ;
TNR4_HUMAN antibody ;
Tumor necrosis factor receptor superfamily member 4 antibody ;
Txgp 1l antibody ;
Txgp1 antibody ;
Txgp1l antibody
show all
Background:
CD134, also known as OX40 and TNFRSF4, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.
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Function:
Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. (Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B.
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Cellular Localization:
Membrane; Single-pass type I membrane protein.
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Tissue Expression:
Expressed by activated B-lymphocytes and monocytes.
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Signaling Pathway
Organismal Systems >> Immune system >> Toll-like receptor signaling pathway
Organismal Systems >> Immune system >> Intestinal immune network for IgA production
Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer
Human Diseases >> Immune disease >> Systemic lupus erythematosus
Human Diseases >> Immune disease >> Rheumatoid arthritis
Human Diseases >> Immune disease >> Autoimmune thyroid disease
Human Diseases >> Immune disease >> Allograft rejection
Human Diseases >> Immune disease >> Graft-versus-host disease
Environmental Information Processing >> Signaling molecules and interaction >> Cell adhesion molecules
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Catalog: YA0545
Size
Price
Status
Qty.
200μg
$600.00
3 weeks
0
100μg
$340.00
3 weeks
0
40μg
$190.00
3 weeks
0
Add to cart
Collected
Collect
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