R

HSP72 (PT1937R) PT™ Rabbit mAb

-YM960236

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Catalog: YM960236
Size
Price
Status
Qty.
200μL
$600.00
3 weeks

0

100μL
$340.00
3 weeks

0

40μL
$190.00
3 weeks

0

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Collected

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Main Information
Target

HSP72

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF, ELISA

MW

70kD (Calculated)

68kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
Endogenous
Purification
Recombinant Antibody  expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
70kD
MW(Observed)
68kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PT1937R
Isotype
IgG,Kappa
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Antigen&Target Information
Immunogen:
The specific immunogen used to produce this antibody is proprietary information.
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Specificity:
Endogenous
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Gene Name:
HSPA2
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Protein Name:
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2)
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Database Link:
Organism Gene ID SwissProt
Human 3306; P54652;
Mouse P17156;
Rat P14659;
Background:
function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with ZNF541.,
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Function:
Function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with ZNF541.,
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Cellular Localization:
Cytoplasm, cytoskeleton, spindle . Colocalizes with SHCBP1L at spindle during the meiosis process. .
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Tissue Expression:
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Research Areas:
>>Spliceosome ;
>>MAPK signaling pathway ;
>>Protein processing in endoplasmic reticulum ;
>>Endocytosis ;
>>Longevity regulating pathway - multiple species ;
>>Antigen processing and presentation ;
>>Estrogen signaling pathway ;
>>Prion disease ;
>>Legionellosis ;
>>Toxoplasmosis ;
>>Measles ;
>>Lipid and atherosclerosis
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Catalog: YM960236
Size
Price
Status
Qty.
200μL
$600.00
3 weeks

0

100μL
$340.00
3 weeks

0

40μL
$190.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service

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