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PTPRR Rabbit pAb

-YT8095

Catalog: YT8095
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$160.00
In stock

0

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Main Information
Target

PTPRR

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

IHC, WB

MW

72kD (Calculated)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-200
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of PTPRR at Human, Mouse,Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
72kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human N-ternal PTPRR
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Specificity:
This antibody detects endogenous levels of PTPRR at Human, Mouse,Rat
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Gene Name:
PTPRR ECPTP PTPRQ
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Protein Name:
Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (Ch-1PTPase) (NC-PTPCOM1) (Protein-tyrosine phosphatase PCPTP1)
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Other Name:
Receptor-type tyrosine-protein phosphatase R ;
R-PTP-R ;
Ch-1PTPase ;
NC-PTPCOM1 ;
Protein-tyrosine phosphatase PCPTP1 ;
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Database Link:
Organism Gene ID SwissProt
Human 5801; Q15256;
Mouse 19279; Q62132;
Rat 94202; O08617;
Function:
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).
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Cellular Localization:
[Isoform Alpha]: Cell membrane; Single-pass type I membrane protein.; [Isoform Delta]: Cytoplasm, perinuclear region. Locates to the perinuclear areas within the cytoplasm.; [Isoform Gamma]: Cytoplasm, perinuclear region. Locates to the perinuclear areas within the cytoplasm.
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Tissue Expression:
Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.
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Catalog: YT8095
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$160.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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