Catalog: YM9511
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
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Main Information
Target
LYPLA1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
25kD (Calculated)
24kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
Endogenous
Purification
Protein A
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
25kD
MW(Observed)
24kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PT1669R
Isotype
IgG,Kappa
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Antigen&Target Information
Specificity:
Endogenous
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Gene Name:
LYPLA1
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Protein Name:
Acyl-protein thioesterase 1
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Other Name:
LYPLA1 ;
APT1 ;
LPL1 ;
Acyl-protein thioesterase 1 ;
APT-1 ;
hAPT1 ;
Lysophospholipase 1 ;
Lysophospholipase I ;
LPL-I ;
LysoPLA I
APT1 ;
LPL1 ;
Acyl-protein thioesterase 1 ;
APT-1 ;
hAPT1 ;
Lysophospholipase 1 ;
Lysophospholipase I ;
LPL-I ;
LysoPLA I
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Database Link:
Background:
This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 4, 6, and 7. [provided by RefSeq, Jul 2013],
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Function:
Catalytic activity:Palmitoyl-protein + H(2)O = palmitate + protein.,Function:Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Also has low lysophospholipase activity.,similarity:Belongs to the AB hydrolase 2 family.,subunit:Homodimer.,
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Cellular Localization:
Cytoplasm . Cell membrane . Nucleus membrane . Endoplasmic reticulum . Shows predominantly a cytoplasmic localization with a weak expression in the cell membrane, nuclear membrane and endoplasmic reticulum. .
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Tissue Expression:
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Research Areas:
>>Glycerophospholipid metabolism ;
>>Choline metabolism in cancer
>>Choline metabolism in cancer
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Reference Citation({{totalcount}})
Catalog: YM9511
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
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