Catalog: YM8133
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
40μL
$190.00
In stock
0
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Collected
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Main Information
Target
FOXP3
Host Species
Rabbit
Reactivity
Human, Mouse, Rat, Pig
Applications
WB, IHC, IF, IP, ELISA
MW
47kD (Calculated)
47kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200,
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
Endogenous
Purification
Protein A
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
47kD
MW(Observed)
47kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PT0211R
Isotype
IgG,Kappa
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RS0002
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Antigen&Target Information
Specificity:
Endogenous
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Gene Name:
FOXP3
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Protein Name:
Forkhead box protein P3
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Other Name:
FOXP3 ;
IPEX ;
JM2 ;
Forkhead box protein P3 ;
Scurfin
IPEX ;
JM2 ;
Forkhead box protein P3 ;
Scurfin
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Background:
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
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Function:
Disease:Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.,Function:Probable transcription factor. Plays a critical role in the control of immune response.,online information:FOXP3 entry,online information:FOXP3 mutation db,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 fork-head DNA-binding domain.,
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Cellular Localization:
Nucleus
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Research Areas:
>>Th17 cell differentiation ;
>>Inflammatory bowel disease
>>Inflammatory bowel disease
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YM8133
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
40μL
$190.00
In stock
0
Add to cart
Collected
Collect
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