Contact Us

408-747-0189
1-877-594-3616

Quick order

Glial Fibrillary Acidic Protein (GFAP) (ABT176) Mouse mAb

-YM4821

Catalog: YM4821
Size
Price
Status
Qty.
200μL
$600.00
In stock

0

100μL
$340.00
In stock

0

40μL
$190.00
In stock

0

Add to cart

Collected

Collect

Customized Service
Main Information
Target

Glial Fibrillary Acidic Protein

Host Species

Mouse

Reactivity

Human, Rat, Monkey, Bovine,

Applications

IHC, WB, IF, ELISA

MW

49kD (Calculated)

50kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
The antibody can specifically recognize human GFAP protein.
Purification
Protein G
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
49kD
MW(Observed)
50kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT176
Isotype
IgG2b,Kappa
Related Products
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001

More→

Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002

More→

Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028

More→

Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029

More→

Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Glial Fibrillary Acidic Protein AA range: 300-432
show all
Specificity:
The antibody can specifically recognize human GFAP protein.
show all
Gene Name:
GFAP
show all
Protein Name:
wu:fb34h11;ALXDRD;cb345;etID36982.3;FLJ42474;FLJ45472;GFAP;GFAP_HUMAN;gfapl;Glial fibrillary acidic protein;Intermediate filament protein;wu:fk42c12;xx:af506734;zgc:110485
show all
Other Name:
wu:fb34h11 ;
ALXDRD ;
cb345 ;
etID36982.3 ;
FLJ42474 ;
FLJ45472 ;
GFAP ;
GFAP_HUMAN ;
gfapl ;
Glial fibrillary acidic protein ;
Intermediate filament protein ;
wu:fk42c12 ;
xx:af506734 ;
zgc:110485
show all
Database Link:
Organism Gene ID SwissProt
Human 2670; P14136;
Mouse P03995;
Rat P47819;
Background:
GFAP is an intermediate filament protein with a molecular weight of 51 kDa, which participates in the formation of cytoskeleton and maintains its tension strength. GFAP is mainly distributed in astrocytes and ependymal cells of the central nervous system, Schwann cells and satellite cells of intestinal ganglion of the peripheral nervous system, myoepithelial cells and chondroblasts. It is mainly used for the diagnosis and differential diagnosis of astrocytoma, including astrocytoma, astroblastoma, mixed glioma, pleomorphic glioblastoma and non astrocytoma, including a few gliomas, most ependymomas and other central nervous system tumors.
show all
Function:
Alternative products:Isoforms differ in the C-terminal region which is encoded by alternative exons,Disease:Defects in GFAP are a cause of Alexander disease (ALEXD) [MIM:203450]. Alexander disease is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes. The most common form affects infants and young children, and is characterized by progressive failure of central myelination, usually leading to death usually within the first decade. Infants with Alexander disease develop a leukoencephalopathy with macrocephaly, seizures, and psychomotor retardation. Patients with juvenile or adult forms typically experience ataxia, bulbar signs and spasticity, and a more slowly progressive course.,Function:GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.,online information:GFAP entry,similarity:Belongs to the intermediate filament family.,subcellular location:Associated with intermediate filaments.,subunit:Interacts with SYNM (By similarity). Isoform 3 interacts with PSEN1 (via N-terminus).,tissue specificity:Expressed in cells lacking fibronectin.,
show all
Cellular Localization:
Cytoplasmic
show all
Tissue Expression:
Brain/ Colon
show all
Research Areas:
>>JAK-STAT signaling pathway
show all
Catalog: YM4821
Size
Price
Status
Qty.
200μL
$600.00
In stock

0

100μL
$340.00
In stock

0

40μL
$190.00
In stock

0

Add to cart

Collected

Collect

Customized Service

Toggle night Mode

{{pinfoXq.title || ''}}

Catalog: {{pinfoXq.catalog || ''}}
Filter:

All

{{item.name}}

{{pinfo.title}}
-{{pinfo.catalog}}

Filter:

{{item.descr}}

Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Learn more
Product {{index}}/{{pcount}}
Prev
Next

{{pvTitle}}

Scroll wheel zooms the picture
{{pvDescr}}