Catalog: YN0302
Size
Price
Status
Qty.
200μL
$450.00
3 weeks
0
100μL
$280.00
3 weeks
0
40μL
$150.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
CIDEA
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
24kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
CIDEA Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year (Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
24kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 140-220
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Specificity:
CIDEA Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
CIDEA
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Protein Name:
Cell death activator CIDE-A (Cell death-inducing DFFA-like effector A)
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Background:
cell death-inducing DFFA-like effector a (CIDEA) Homo sapiens This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates , higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq , Aug 2010] ,
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Function:
Function:Activates apoptosis. ,similarity:Contains 1 CIDE-N domain. ,subunit:Inhibited by DFFB. ,
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Cellular Localization:
Lipid droplet . Nucleus . Enriched at lipid droplet contact sites. Has been shown to localize to mitochondria , where it could interact with UCP1 and hence inhibit UCP1 uncoupling activity (By similarity) . These data could not be confirmed (PubMed:18509062) . .
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Tissue Expression:
Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN0302
Size
Price
Status
Qty.
200μL
$450.00
3 weeks
0
100μL
$280.00
3 weeks
0
40μL
$150.00
3 weeks
0
Add to cart
Collected
Collect
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