Catalog: YM4777
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
SRp20
Host Species
Mouse
Reactivity
Human, Mouse
Applications
WB, IF, ELISA
MW
19kD (Calculated)
19kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
This antibody detects endogenous levels of SRSF3.
Purification
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
Storage
-15°C to -25°C/1 year (Do not lower than -25°C)
MW(Calculated)
19kD
MW(Observed)
19kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PTR1361
Isotype
Mouse IgG1/Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein.AA range: 100-200
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Specificity:
This antibody detects endogenous levels of SRSF3.
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Gene Name:
SRSF3
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Protein Name:
Serine/arginine-rich splicing factor 3
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Other Name:
SRSF3 ;
SFRS3 ;
SRP20 ;
Serine/arginine-rich splicing factor 3 ;
Pre-mRNA-splicing factor SRP20 ;
Splicing factor ;
arginine/serine-rich 3
SFRS3 ;
SRP20 ;
Serine/arginine-rich splicing factor 3 ;
Pre-mRNA-splicing factor SRP20 ;
Splicing factor ;
arginine/serine-rich 3
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Background:
The protein encoded by this gene is a member of the serine/arginine (SR) -rich family of pre-mRNA splicing factors , which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing , the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants , one protein-coding and the other non-coding , have been found for this gene. [provided by RefSeq , Sep 2010] ,
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Function:
Function:May be involved in RNA processing in relation with cellular proliferation and/or maturation. ,PTM:Extensively phosphorylated on serine residues in the RS domain. ,similarity:Belongs to the splicing factor SR family. ,similarity:Contains 1 RRM (RNA recognition motif) domain. ,subunit:Interacts with CPSF6 , RBMY1A1 and SFRS12. ,
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Tissue Expression:
Research Areas:
>>Spliceosome ;
>>Amyotrophic lateral sclerosis ;
>>Herpes simplex virus 1 infection
>>Amyotrophic lateral sclerosis ;
>>Herpes simplex virus 1 infection
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Reference Citation({{totalcount}})
Catalog: YM4777
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
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