Catalog: YM4937
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
N-Cadherin
Host Species
Mouse
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
100kD (Calculated)
110kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:100-500; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
This antibody detects endogenous levels of N-Cadherin protein.
Purification
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
Storage
-15°C to -25°C/1 year (Do not lower than -25°C)
MW(Calculated)
100kD
MW(Observed)
110kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT-CDH2
Isotype
Mouse IgG2b/Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human N-Cadherin AA range: 200-400
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Specificity:
This antibody detects endogenous levels of N-Cadherin protein.
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Gene Name:
CDH2 CDHN NCAD
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Protein Name:
Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)
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Database Link:
Background:
This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants , at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry , development of the nervous system and the formation of cartilage and bone. [provided by RefSeq , Nov 2015] ,
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Function:
Function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. ,similarity:Contains 5 cadherin domains. ,subunit:Interacts with CDCP1. ,
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Cellular Localization:
Membranous
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Tissue Expression:
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Research Areas:
>>Cell adhesion molecules ;
>>Arrhythmogenic right ventricular cardiomyopathy
>>Arrhythmogenic right ventricular cardiomyopathy
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YM4937
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
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