The specific immunogen used to produce this antibody is proprietary information.

Endogenous

CD28

T-cell-specific surface glycoprotein CD28

CD28 ;
T-cell-specific surface glycoprotein CD28 ;
TP44 ;
CD28

The protein encoded by this gene is essential for T-cell proliferation and survival , cytokine production , and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq , Jul 2011] ,

Function:Involved in T-cell activation , the induction of cell proliferation and cytokine production and promotion of T-cell survival. ,online information:CD28 entry ,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain. ,subunit:Homodimer; disulfide-linked. Interacts with DUSP14. Binds to CD80/B7-1 and CD86/B7-2/B70. ,tissue specificity:Expressed in T-cells and plasma cells , but not in less mature B-cells. ,

Membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell surface .

>>Cell adhesion molecules ;
>>T cell receptor signaling pathway ;
>>Intestinal immune network for IgA production ;
>>Type I diabetes mellitus ;
>>Measles ;
>>PD-L1 expression and PD-1 checkpoint pathway in cancer ;
>>Autoimmune thyroid disease ;
>>Systemic lupus erythematosus ;
>>Rheumatoid arthritis ;
>>Allograft rejection ;
>>Graft-versus-host disease ;
>>Viral myocarditis