USP24 Polyclonal Antibody

    • Catalog No.:YT4833
    • Applications:IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • USP24
      • Gene Name:
      • USP24
      • Protein Name:
      • Ubiquitin carboxyl-terminal hydrolase 24
      • Human Swiss Prot No:
      • Q9UPU5
      • Mouse Swiss Prot No:
      • B1AY13
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human USP24. AA range:21-70
      • Specificity:
      • USP24 Polyclonal Antibody detects endogenous levels of USP24 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • USP24;KIAA1057;Ubiquitin carboxyl-terminal hydrolase 24;Deubiquitinating enzyme 24;Ubiquitin thioesterase 24;Ubiquitin-specific-processing protease 24
      • Molecular Weight(Da):
      • 211kD
      • Background:
      • Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],
      • Function:
      • catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UBA domain.,
      • Subcellular Location:
      • cytoplasm,
      • Expression:
      • Brain,Epithelium,Placenta,Platelet,T-cell,
      • Products Images
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using USP24 Antibody. The picture on the right is blocked with the synthesized peptide.