TMEM16A Polyclonal Antibody

    • Catalog No.:YT4679
    • Applications:IF;ELISA
    • Reactivity:Human;Mouse;
      • Target:
      • TMEM16A
      • Gene Name:
      • ANO1
      • Protein Name:
      • Anoctamin-1
      • Human Swiss Prot No:
      • Q5XXA6
      • Mouse Swiss Prot No:
      • Q8BHY3
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human TM16A. AA range:921-970
      • Specificity:
      • TMEM16A Polyclonal Antibody detects endogenous levels of TMEM16A protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • ANO1;DOG1;ORAOV2;TAOS2;TMEM16A;Anoctamin-1;Discovered on gastrointestinal stromal tumors protein 1;Oral cancer overexpressed protein 2;Transmembrane protein 16A;Tumor-amplified and overexpressed sequence 2
      • Molecular Weight(Da):
      • 114kD
      • Background:
      • domain:The region spanning the fifth and sixth transmembrane domains probably forms the pore-forming region.,function:Acts as a calcium-activated chloride channel. Required for normal tracheal development.,similarity:Belongs to the anoctamin family.,tissue specificity:Broadly expressed with higher levels in liver and skeletal muscle.,
      • Function:
      • domain:The region spanning the fifth and sixth transmembrane domains probably forms the pore-forming region.,function:Acts as a calcium-activated chloride channel. Required for normal tracheal development.,similarity:Belongs to the anoctamin family.,tissue specificity:Broadly expressed with higher levels in liver and skeletal muscle.,
      • Subcellular Location:
      • Cell membrane ; Multi-pass membrane protein . Cytoplasm . Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors. .
      • Expression:
      • Broadly expressed with higher levels in liver, skeletal muscle and gastrointestinal muscles.
      • Products Images
      • Immunofluorescence analysis of HeLa cells, using TM16A Antibody. The picture on the right is blocked with the synthesized peptide.