SSTR4 Polyclonal Antibody

    • Catalog No.:YT4430
    • Applications:WB;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • SSTR4
      • Fields:
      • >>Neuroactive ligand-receptor interaction
      • Gene Name:
      • SSTR4
      • Protein Name:
      • Somatostatin receptor type 4
      • Human Gene Id:
      • 6754
      • Human Swiss Prot No:
      • P31391
      • Mouse Swiss Prot No:
      • P49660
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human SSTR4. AA range:155-204
      • Specificity:
      • SSTR4 Polyclonal Antibody detects endogenous levels of SSTR4 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SSTR4;Somatostatin receptor type 4;SS-4-R;SS4-R;SS4R
      • Observed Band(KD):
      • 42kD
      • Background:
      • Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung. [provided by RefSeq, Jul 2008],
      • Function:
      • function:Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.,
      • Subcellular Location:
      • Cell membrane; Multi-pass membrane protein.
      • Expression:
      • Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.
      • Products Images
      • Western blot analysis of lysates from LOVO cells, using SSTR4 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HepG2 cells using SSTR4 antibody.