Six2 Polyclonal Antibody

    • Catalog No.:YT4306
    • Applications:WB;IHC
    • Reactivity:Human;Mouse
      • Target:
      • Six2
      • Gene Name:
      • SIX2
      • Protein Name:
      • Homeobox protein SIX2
      • Human Swiss Prot No:
      • Q9NPC8
      • Mouse Swiss Prot No:
      • Q62232
      • Immunogen:
      • Synthesized peptide derived from Six2 . at AA range: 30-110
      • Specificity:
      • Six2 Polyclonal Antibody detects endogenous levels of Six2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SIX2;Homeobox protein SIX2;Sine oculis homeobox homolog 2
      • Observed Band(KD):
      • 33kD
      • Background:
      • This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. The encoded protein is a transcription factor which, like other members of this gene family, may be involved in limb or eye development. [provided by RefSeq, Dec 2008],
      • Function:
      • function:May be involved in limb tendon and ligament development.,similarity:Belongs to the SIX/Sine oculis homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Strongly expressed in skeletal muscle.,
      • Subcellular Location:
      • Nucleus .
      • Expression:
      • Strongly expressed in skeletal muscle. Expressed in Wilms' tumor and in the cap mesenchyme of fetal kidney (at protein level).
      • Products Images
      • Western blot analysis of SIX2 Antibody. The lane on the right is blocked with the SIX2 peptide.
      • Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).