SERGEF Polyclonal Antibody

    • Catalog No.:YT4254
    • Applications:WB;ELISA;IHC
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • SERGEF
      • Gene Name:
      • SERGEF
      • Protein Name:
      • Secretion-regulating guanine nucleotide exchange factor
      • Human Swiss Prot No:
      • Q9UGK8
      • Mouse Swiss Prot No:
      • Q80YD6
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human SERGEF. AA range:179-228
      • Specificity:
      • SERGEF Polyclonal Antibody detects endogenous levels of SERGEF protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SERGEF;DELGEF;GNEFR;Secretion-regulating guanine nucleotide exchange factor;Deafness locus-associated putative guanine nucleotide exchange factor;DelGEF;Guanine nucleotide exchange factor-related protein
      • Observed Band(KD):
      • 50kD
      • Background:
      • function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.,
      • Function:
      • function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.,
      • Subcellular Location:
      • Cytoplasm . Nucleus .
      • Expression:
      • Fetal brain,Ovary,
      • Products Images
      • Western blot analysis of SERGEF Antibody. The lane on the right is blocked with the SERGEF peptide.
      • Western blot analysis of the lysates from HT-29 cells using SERGEF antibody.
      • Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).