SENP8 Polyclonal Antibody

    • Catalog No.:YT4242
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • SENP8
      • Gene Name:
      • SENP8
      • Protein Name:
      • Sentrin-specific protease 8
      • Human Swiss Prot No:
      • Q96LD8
      • Mouse Swiss Prot No:
      • Q9D2Z4
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human SENP8. AA range:161-210
      • Specificity:
      • SENP8 Polyclonal Antibody detects endogenous levels of SENP8 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SENP8;DEN1;NEDP1;PRSC2;FKSG8;Sentrin-specific protease 8;Deneddylase-1;NEDD8-specific protease 1;Protease; cysteine 2;Sentrin/SUMO-specific protease SENP8
      • Observed Band(KD):
      • 27kD
      • Background:
      • This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],
      • Function:
      • function:Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.,similarity:Belongs to the peptidase C48 family.,tissue specificity:Broadly expressed, with highest levels in kidney and pancreas.,
      • Expression:
      • Broadly expressed, with highest levels in kidney and pancreas.
      • Products Images
      • Western Blot analysis of various cells using SENP8 Polyclonal Antibody
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SENP8 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from HUVEC cells, using SENP8 Antibody. The lane on the right is blocked with the synthesized peptide.