Rab 24 Polyclonal Antibody

    • Catalog No.:YT3923
    • Applications:IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Rab 24
      • Gene Name:
      • RAB24
      • Protein Name:
      • Ras-related protein Rab-24
      • Human Swiss Prot No:
      • Q969Q5
      • Mouse Swiss Prot No:
      • P35290
      • Immunogen:
      • Synthesized peptide derived from Rab 24 . at AA range: 90-170
      • Specificity:
      • Rab 24 Polyclonal Antibody detects endogenous levels of Rab 24 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000 ,IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • RAB24;Ras-related protein Rab-24
      • Molecular Weight(Da):
      • 23kD
      • Background:
      • RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009],
      • Function:
      • function:May be involved in autophagy-related processes.,induction:By extensive retinoic acid treatment, in Ntera-2 teratoma cell line induced to differentiate into post-mitotic neurons (NTN2) (at protein level).,miscellaneous:The unusual Ser-67, instead of a conserved Gln in other family members, is the cause of low GTPase activity. As a result, the predominant nucleotide associated with the protein is GTP.,PTM:Isoprenylation is inefficient compared to other Rab family members.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Only about 20-25% is recovered in the particulate fraction.,subunit:Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including ARHGDIA and ARHGDIB.,
      • Subcellular Location:
      • Cytoplasm, cytosol . Membrane ; Lipid-anchor . Only about 20-25% is recovered in the particulate fraction. .
      • Expression:
      • Amygdala,Pancreas,Skin,Uterus,Whole embryo,
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).