Rab 24 Polyclonal Antibody

  • Catalog No.:YT3923
  • Applications:IHC-p,IF(paraffin section),ELISA
  • Reactivity:Human,Mouse,Rat
    • Gene Name:
    • RAB24
    • Protein Name:
    • Ras-related protein Rab-24
    • Human Swiss Prot No:
    • Q969Q5
    • Mouse Swiss Prot No:
    • P35290
    • Immunogen:
    • Synthesized peptide derived from Rab 24 . at AA range: 90-170
    • Specificity:
    • Rab 24 Polyclonal Antibody detects endogenous levels of Rab 24 protein.
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • RAB24; Ras-related protein Rab-24
    • MolecularWeight(Da):
    • 23124
    • Background:
    • RAB24, member RAS oncogene family(RAB24) Homo sapiens RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009],
    • Function:
    • function:May be involved in autophagy-related processes.,induction:By extensive retinoic acid treatment, in Ntera-2 teratoma cell line induced to differentiate into post-mitotic neurons (NTN2) (at protein level).,miscellaneous:The unusual Ser-67, instead of a conserved Gln in other family members, is the cause of low GTPase activity. As a result, the predominant nucleotide associated with the protein is GTP.,PTM:Isoprenylation is inefficient compared to other Rab family members.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Only about 20-25% is recovered in the particulate fraction.,subunit:Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including ARHGDIA and ARHGDIB.,
    • Subcellular Location:
    • intracellular,mitochondrion,autophagosome,cytosol,membrane,
    • Expression:
    • Amygdala,Pancreas,Skin,Uterus,Whole embryo,