• Gene Name：
• RAB1B

• Protein Name：
• Ras-related protein Rab-1B

• Human Gene Id：
• 81876

• Human Swiss Prot No：
• Q9H0U4

• Mouse Gene Id：
• 76308

• Mouse Swiss Prot No：
• Q9D1G1

• Rat Swiss Prot No：
• P10536

• Immunogen：
• Synthesized peptide derived from Rab 1B . at AA range: 50-130

• Specificity：
• Rab 1B Polyclonal Antibody detects endogenous levels of Rab 1B protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Rabbit

• Dilution：
• Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -20°C/1 year

• Other Name：
• RAB1B; Ras-related protein Rab-1B

• MolecularWeight(Da)：
• 22171

• Observed Band(KD)：
• 22

• Background：
• RAB1B, member RAS oncogene family(RAB1B) Homo sapiens Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009],

• Function：
• function:Protein transport. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments.,miscellaneous:Rab-1B binds GTP and GDP and possesses intrinsic GTPase activity.,PTM:Prenylated; by GGTase II, only after interaction of the substrate with Rab escort protein 1 (REP1).,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Targeted by REP1 to membranes of specific subcellular compartments including endoplasmic reticulum, Golgi apparatus, and intermediate vesicles between these two compartments. In the GDP-form, colocalizes with GDI in the cytoplasm.,subunit:Interacts with MICAL1, MICAL2 and MICAL3. Interacts with GDI1; the interaction requires the GDP-bound state. Interacts with CHM/REP1; the interaction requires the GDP-bound form and is necessary for prenylation by GGTase II.,

• Subcellular Location：
• Golgi membrane,intracellular,mitochondrion,endoplasmic reticulum membrane,Golgi apparatus,transport vesicle,endoplasmic reticulum-Golgi intermediate compartment membrane,pre-autophagosomal structure membrane,extracellular exosome,

• Expression：
• B-cell lymphoma,Brain,Muscle,Pancreas,

• June 19-2018
• WESTERN IMMUNOBLOTTING PROTOCOL

• June 19-2018
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• June 19-2018
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• July 13-2018
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• July 13-2018
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• July 13-2018
• Antibody-FAQs