Rab 18 Polyclonal Antibody

    • Catalog No.:YT3920
    • Applications:WB;ELISA;IHC
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Rab 18
      • Gene Name:
      • RAB18
      • Protein Name:
      • Ras-related protein Rab-18
      • Human Swiss Prot No:
      • Q9NP72
      • Mouse Swiss Prot No:
      • P35293
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human RAB18. AA range:103-152
      • Specificity:
      • Rab 18 Polyclonal Antibody detects endogenous levels of Rab 18 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • RAB18;Ras-related protein Rab-18
      • Observed Band(KD):
      • 28kD
      • Background:
      • The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
      • Function:
      • function:Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous.,
      • Subcellular Location:
      • Apical cell membrane . Lipid droplet .
      • Expression:
      • Ubiquitous.
      • Products Images
      • Western Blot analysis of MCF-7 cells using Rab 18 Polyclonal Antibody
      • Western blot analysis of lysates from MCF-7 and HUVEC cells, using RAB18 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HepG2 cells using RAB18 antibody.
      • Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).