PREP-2 Polyclonal Antibody

    • Catalog No.:YT3855
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • PREP-2
      • Gene Name:
      • PKNOX2
      • Protein Name:
      • Homeobox protein PKNOX2
      • Human Swiss Prot No:
      • Q96KN3
      • Mouse Swiss Prot No:
      • Q8BG99
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human PKNOX2. AA range:341-390
      • Specificity:
      • PREP-2 Polyclonal Antibody detects endogenous levels of PREP-2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • PKNOX2;PREP2;Homeobox protein PKNOX2;Homeobox protein PREP-2;PBX/knotted homeobox 2
      • Observed Band(KD):
      • 55kD
      • Background:
      • Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 [PubMed 11549286]).[supplied by OMIM, Oct 2009],
      • Function:
      • similarity:Belongs to the TALE/MEIS homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
      • Subcellular Location:
      • Nucleus .
      • Expression:
      • Brain,Small intestine,
      • Products Images
      • Western Blot analysis of various cells using PREP-2 Polyclonal Antibody
      • Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
      • Western blot analysis of lysates from HepG2 cells, using PKNOX2 Antibody. The lane on the right is blocked with the synthesized peptide.