Oncogene TIM Polyclonal Antibody

    • Catalog No.:YT3461
    • Applications:WB,ELISA
    • Reactivity:Human,Mouse,Rat
      • Gene Name:
      • ARHGEF5
      • Protein Name:
      • Rho guanine nucleotide exchange factor 5
      • Human Gene Id:
      • 7984
      • Human Swiss Prot No:
      • Q12774
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human ARHGEF5. AA range:191-240
      • Specificity:
      • Oncogene TIM Polyclonal Antibody detects endogenous levels of Oncogene TIM protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • ARHGEF5; TIM; Rho guanine nucleotide exchange factor 5; Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; Transforming immortalized mammary oncogene; p60 TIM
      • MolecularWeight(Da):
      • 60056
      • Observed Band(KD):
      • 60
      • Background:
      • Rho guanine nucleotide exchange factor 5(ARHGEF5) Homo sapiens Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008],
      • Function:
      • similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Mainly expressed in kidney, liver, pancreas, lung and placenta.,
      • Subcellular Location:
      • podosome,intracellular,nucleus,nucleoplasm,cytoplasm,plasma membrane,cell junction,cell projection,cell periphery,
      • Expression:
      • Endometrium carcinoma cell line,Epithelium,Placenta,Skin,Sp
      • Products Images
      • Western blot analysis of lysates from RAW264.7 cells, using ARHGEF5 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from K562 cells using ARHGEF5 antibody.