OB-cadherin Polyclonal Antibody

    • Catalog No.:YT3224
    • Applications:WB;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • OB-cadherin
      • Gene Name:
      • CDH11
      • Protein Name:
      • Cadherin-11
      • Human Gene Id:
      • 1009
      • Human Swiss Prot No:
      • P55287
      • Mouse Swiss Prot No:
      • P55288
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human CDH11. AA range:421-470
      • Specificity:
      • OB-cadherin Polyclonal Antibody detects endogenous levels of OB-cadherin protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CDH11;Cadherin-11;OSF-4;Osteoblast cadherin;OB-cadherin
      • Observed Band(KD):
      • 85kD
      • Background:
      • This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008],
      • Function:
      • function:Cadherins are calcium dependent cell adhesion proteins.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts.,
      • Subcellular Location:
      • Cell membrane; Single-pass type I membrane protein.
      • Expression:
      • Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts.
      • Products Images
      • Western Blot analysis of Jurkat cells using OB-cadherin Polyclonal Antibody
      • Western blot analysis of lysates from Jurkat cells, using CDH11 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HeLa cells using Cytochrome P450 1A1/2 antibody.