NRBF-2 Polyclonal Antibody

    • Catalog No.:YT3187
    • Applications:WB;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • NRBF-2
      • Fields:
      • >>Autophagy - animal;>>Alzheimer disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Pathways of neurodegeneration - multiple diseases
      • Gene Name:
      • NRBF2
      • Protein Name:
      • Nuclear receptor-binding factor 2
      • Human Swiss Prot No:
      • Q96F24
      • Mouse Swiss Prot No:
      • Q8VCQ3
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human NRBF2. AA range:140-189
      • Specificity:
      • NRBF-2 Polyclonal Antibody detects endogenous levels of NRBF-2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • NRBF2;COPR;Nuclear receptor-binding factor 2;NRBF-2;Comodulator of PPAR and RXR
      • Observed Band(KD):
      • 36kD
      • Background:
      • function:May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).,subunit:Interacts with PPARA, PPARD and PPARG. Interacts with RARA, RARG and RXRA in the presence of bound ligand.,tissue specificity:Detected in keratinocytes, liver and placenta.,
      • Function:
      • function:May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).,subunit:Interacts with PPARA, PPARD and PPARG. Interacts with RARA, RARG and RXRA in the presence of bound ligand.,tissue specificity:Detected in keratinocytes, liver and placenta.,
      • Subcellular Location:
      • Nucleus . Cytoplasm . Cytoplasmic vesicle . Cytoplasmic vesicle, autophagosome .
      • Expression:
      • Detected in keratinocytes, liver and placenta (PubMed:15610520). Expressed in a subset of cells in pediatric medulloblastoma (PubMed:18619852).
      • Products Images
      • Western Blot analysis of various cells using NRBF-2 Polyclonal Antibody
      • Western blot analysis of lysates from A549 cells, using NRBF2 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from RAW264.7cells using NRBF2 antibody.