NOC2L Polyclonal Antibody

    • Catalog No.:YT3160
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • NOC2L
      • Gene Name:
      • NOC2L
      • Protein Name:
      • Nucleolar complex protein 2 homolog
      • Human Swiss Prot No:
      • Q9Y3T9
      • Mouse Swiss Prot No:
      • Q9WV70
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human NOC2L. AA range:602-651
      • Specificity:
      • NOC2L Polyclonal Antibody detects endogenous levels of NOC2L protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • NOC2L;NIR;Nucleolar complex protein 2 homolog;Protein NOC2 homolog;NOC2-like protein;Novel INHAT repressor
      • Observed Band(KD):
      • 85kD
      • Background:
      • NOC2 like nucleolar associated transcriptional repressor(NOC2L) Homo sapiens Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]).[supplied by OMIM, Mar 2008],
      • Function:
      • similarity:Belongs to the NOC2 family.,
      • Subcellular Location:
      • Nucleus, nucleoplasm. Nucleus, nucleolus. Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin-D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis.
      • Expression:
      • Brain,Epithelium,Placenta,
      • Products Images
      • Gong, Yanqiu, et al. "Age-Associated Proteomic Signatures and Potential Clinically Actionable Targets of Colorectal Cancer." Molecular & Cellular Proteomics (2021): 100115.
      • Western blot analysis of lysates from MCF-7 cells, using NOC2L Antibody. The lane on the right is blocked with the synthesized peptide.