Mos Polyclonal Antibody

    • Catalog No.:YT2818
    • Applications:WB;ELISA;IHC
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • Mos
      • Fields:
      • >>Oocyte meiosis;>>Regulation of actin cytoskeleton;>>Progesterone-mediated oocyte maturation
      • Gene Name:
      • MOS
      • Protein Name:
      • Proto-oncogene serine/threonine-protein kinase mos
      • Human Gene Id:
      • 4342
      • Human Swiss Prot No:
      • P00540
      • Mouse Swiss Prot No:
      • P00536
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human MOS. AA range:61-110
      • Specificity:
      • Mos Polyclonal Antibody detects endogenous levels of Mos protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • MOS;Proto-oncogene serine/threonine-protein kinase mos;Oocyte maturation factor mos;Proto-oncogene c-Mos
      • Observed Band(KD):
      • 40kD
      • Background:
      • MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).[supplied by OMIM, Jul 2009],
      • Function:
      • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed specifically in testis during spermatogenesis.,
      • Subcellular Location:
      • intracellular,
      • Expression:
      • Expressed specifically in testis during spermatogenesis.
      • Products Images
      • Western Blot analysis of various cells using Mos Polyclonal Antibody
      • Western blot analysis of lysates from 293 cells, using MOS Antibody. The lane on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human uterus. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).