• Target：
• MafF

• Gene Name：
• MAFF

• Protein Name：
• Transcription factor MafF

• Human Gene Id：
• 23764

• Human Swiss Prot No：
• Q9ULX9

• Mouse Gene Id：
• 17133

• Mouse Swiss Prot No：
• O54791

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human MAFF. AA range:51-100

• Specificity：
• MafF Polyclonal Antibody detects endogenous levels of MafF protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• MAFF;Transcription factor MafF;U-Maf;V-maf musculoaponeurotic fibrosarcoma oncogene homolog F

• Molecular Weight(Da)：
• 18kD

• Background：
• The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009],

• Function：
• function:Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. Since it lacks a putative transactivation domain, it may behave as a transcriptional repressor when it dimerize among himself. May also serve as a transcriptional activator by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. May be involved in the cellular stress response.,induction:By oxidative stress.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Maf subfamily.,similarity:Contains 1 bZIP domain.,subunit:Monomer and homo- or heterodimer. Interacts with MIP.,tissue specificity:Expressed in the term myometrium and kidney.,

• Subcellular Location：
• Nucleus.

• Expression：
• Expressed in the term myometrium and kidney.

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