KKIAMRE Polyclonal Antibody

    • Catalog No.:YT2482
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • KKIAMRE
      • Gene Name:
      • CDKL2
      • Protein Name:
      • Cyclin-dependent kinase-like 2
      • Human Gene Id:
      • 8999
      • Human Swiss Prot No:
      • Q92772
      • Mouse Swiss Prot No:
      • Q9QUK0
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human CDKL2. AA range:211-260
      • Specificity:
      • KKIAMRE Polyclonal Antibody detects endogenous levels of KKIAMRE protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CDKL2;Cyclin-dependent kinase-like 2;Protein kinase p56 KKIAMRE;Serine/threonine-protein kinase KKIAMRE
      • Observed Band(KD):
      • 56kD
      • Background:
      • This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008],
      • Function:
      • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The [NKR]KIAxRE motif seems to be a cyclin-binding region.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in testis and kidney, and at lower level in brain and lung.,
      • Subcellular Location:
      • Cytoplasm . Nucleus .
      • Expression:
      • Expressed in testis and kidney, and at lower level in brain and lung.
      • Products Images
      • Western blot analysis of lysates from Jurkat and 293 cells, using CDKL2 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).