GBP4 Polyclonal Antibody

    • Catalog No.:YT1869
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • GBP4
      • Fields:
      • >>NOD-like receptor signaling pathway
      • Gene Name:
      • GBP4
      • Protein Name:
      • Guanylate-binding protein 4
      • Human Swiss Prot No:
      • Q96PP9
      • Mouse Swiss Prot No:
      • Q61107
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human GBP4. AA range:551-600
      • Specificity:
      • GBP4 Polyclonal Antibody detects endogenous levels of GBP4 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • GBP4;Guanylate-binding protein 4;GTP-binding protein 4;GBP-4;Guanine nucleotide-binding protein 4
      • Observed Band(KD):
      • 73kD
      • Background:
      • Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008],
      • Function:
      • function:Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation.,similarity:Belongs to the GBP family.,
      • Subcellular Location:
      • Cytoplasm . Nucleus . Cytoplasm, perinuclear region . Golgi apparatus membrane . Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. .
      • Expression:
      • Brain,Epithelium,Placenta,Spinal cord,Spleen,Testis,
      • Products Images
      • Western Blot analysis of RAW cells using GBP4 Polyclonal Antibody
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using GBP4 Antibody. The picture on the right is blocked with the synthesized peptide.