• Target：
• Dynein LC 4

• Fields：
• >>Amyotrophic lateral sclerosis;>>Huntington disease;>>Pathways of neurodegeneration - multiple diseases

• Gene Name：
• DNAL4

• Protein Name：
• Dynein light chain 4 axonemal

• Human Gene Id：
• 10126

• Human Swiss Prot No：
• O96015

• Mouse Gene Id：
• 54152

• Mouse Swiss Prot No：
• Q9DCM4

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human DNAL4. AA range:1-50

• Specificity：
• Dynein LC 4 Polyclonal Antibody detects endogenous levels of Dynein LC 4 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• DNAL4;Dynein light chain 4; axonemal

• Molecular Weight(Da)：
• 12kD

• Background：
• This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. [provided by RefSeq, Dec 2014],

• Function：
• function:Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.,similarity:Belongs to the dynein light chain family.,subunit:Consists of at least two heavy chains and a number of intermediate and light chains.,

• Subcellular Location：
• Cytoplasm, cytoskeleton, cilium axoneme .

• Expression：
• Lung,Skin,Testis,

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