• Target：
• CLLD7

• Gene Name：
• RCBTB1

• Protein Name：
• RCC1 and BTB domain-containing protein 1

• Human Gene Id：
• 55213

• Human Swiss Prot No：
• Q8NDN9

• Mouse Gene Id：
• 71330

• Mouse Swiss Prot No：
• Q6NXM2

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human RCBTB1. AA range:251-300

• Specificity：
• CLLD7 Polyclonal Antibody detects endogenous levels of CLLD7 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• RCBTB1;CLLD7;E4.5;RCC1 and BTB domain-containing protein 1;Chronic lymphocytic leukemia deletion region gene 7 protein;CLL deletion region gene 7 protein;Regulator of chromosome condensation and BTB domain-containing protein 1

• Observed Band(KD)：
• 58kD

• Background：
• This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008],

• Function：
• function:May be involved in cell cycle regulation by chromatin remodeling.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 2 BTB (POZ) domains.,similarity:Contains 6 RCC1 repeats.,tissue specificity:Ubiquitously expressed.,

• Subcellular Location：
• Nucleus .

• Expression：
• Ubiquitously expressed (PubMed:11306461, PubMed:27486781). In the retina, present in the nerve fiber layer and to a lesser extent in the inner and outer plexiform layers (at protein level) (PubMed:27486781).

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